DNA methylation testing for biological age is highly accurate, with studies showing correlations of 85-95% between methylation patterns and actual aging markers. These tests use validated algorithms based on hundreds of methylation sites across your genome, providing a more precise measure of cellular aging than traditional biomarkers. However, results should be interpreted alongside other health assessments, as individual variations exist. The accuracy makes methylation testing one of the most reliable methods currently available for determining biological versus chronological age.

DNA methylation testing is performed using a simple at-home cheek swab or saliva collection kit. After ordering online, you receive a collection kit with clear instructions – such as swab the inside of your cheek for 30 seconds, place the sample in the provided tube, and mail it back using the prepaid shipping label. Laboratory analysis typically takes 3-6 weeks, after which you receive detailed digital results explaining your biological age and personalised health recommendations based on your methylation patterns.

Genetic testing analyses your DNA sequence to identify inherited variants that remain constant throughout life, while DNA methylation testing examines epigenetic modifications that change over time based on lifestyle and environment. Genetic tests reveal your predispositions and traits encoded in your genes, whereas methylation testing shows how your genes are currently being expressed and how this affects your biological aging. Think of genetic testing as your blueprint, while methylation testing shows how that blueprint is being used by your cells right now.

Yes, DNA methylation patterns can be modified through targeted lifestyle interventions, making this one of the most actionable forms of health testing. Research shows that changes in diet, exercise, stress management, sleep quality, and specific supplements can positively influence methylation patterns and potentially slow biological aging. Unlike genetic mutations, methylation changes are reversible, meaning you can actively work to improve your biological age through evidence-based interventions tailored to your test results.

DNA methylation testing is ideal for health-conscious individuals aged 30 and above who want to understand their aging process and optimise longevity. It's particularly valuable for people with family histories of age-related diseases, those experiencing premature aging signs, fitness enthusiasts wanting to optimise performance, and anyone interested in personalised anti-aging strategies. The test is also beneficial for individuals considering preventive healthcare approaches or those already following wellness protocols who want to measure their effectiveness.

Most experts recommend repeating DNA methylation testing every 1-2 years to track changes in biological age and assess the effectiveness of lifestyle interventions. Since methylation patterns can change relatively quickly in response to diet, exercise, and lifestyle modifications, annual testing allows you to monitor progress and adjust your health strategies accordingly. Some individuals may benefit from more frequent testing (every 6-12 months) if implementing significant lifestyle changes or following specific anti-aging protocols.

Currently, most insurance plans do not cover DNA methylation testing for biological age assessment, as these tests are considered preventive or wellness-focused rather than diagnostic. As the science advances and becomes more mainstream, insurance coverage may expand in the future.

Multiple lifestyle factors significantly influence DNA methylation patterns, including diet quality (particularly folate, B vitamins, and antioxidants), regular exercise, stress management, sleep duration and quality, alcohol consumption, smoking, environmental toxin exposure, and social connections. Positive factors like Mediterranean diets, regular physical activity, meditation, and quality sleep can improve methylation patterns and slow biological aging, while chronic stress, poor diet, and toxin exposure can accelerate cellular aging.

DNA methylation test results typically show your biological age compared to your chronological age, along with explanations of what this means for your health and longevity. Reports include personalised recommendations for diet, supplements, exercise, and lifestyle changes based on your specific methylation patterns.

Our genetic tests are conducted in a CLIA certified laboratory. The protocols we use are suitable for genetic research only, not for clinical genetic testing like you would receive at a hospital or doctor’s office. Clinical genetic testing is held to higher standards and is done in laboratories, which are certified by governmental regulations called CLIA (Clinical Laboratory Improvement Amendments).