Description
Provider: Cyrex laboratory
Description
This panel assesses the integrity of both the intestinal and blood-brain barriers and evaluates immune responses associated with small intestinal bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS). It provides insights into the gut-brain axis and its role in systemic and neurological health.
Test Targets
Array 2: Tight junction proteins (occludin, zonulin), actomyosin, lipopolysaccharides (LPS).
Array 20: Blood-brain barrier proteins.
Array 22: Bacterial cytotoxins and cytoskeletal proteins.
Method / Analytes
Method: Enzyme-Linked Immunosorbent Assay (ELISA) detecting IgG, IgA, and IgM antibodies.
Antibody Class: IgG, IgA, IgM
Clinical Use
Evaluates intestinal permeability, which can contribute to systemic inflammation and autoimmunity. Assesses the integrity of the blood-brain barrier, aiding in the early detection of neuroinflammatory and neurodegenerative conditions. Identifies immune responses associated with SIBO and IBS, facilitating targeted treatment strategies. Supports the development of comprehensive interventions to restore barrier integrity and manage related health issues.
Pathology Area
Neurology
