Description
Array 5 – Multiple Autoimmune Reactivity Screen
The Array 5 is a broad surveillance test for autoantibodies against multiple organ-specific antigens.
What does this test measure?
It includes a panel of around 24 markers corresponding to various tissues, among which:
- Neurological: MBP (myelin basic protein) for MS, Cerebellar peptides, Gangliosides
- Joint/Collagen: Collagen II, possibly CCP (cyclic citrullinated peptide)
- Thyroid: TPO (thyroid peroxidase), TGB (thyroglobulin)
- Pancreas: GAD65 (glutamic acid decarboxylase)
- Adrenal: 21-hydroxylase
- Reproductive: Ovarian/testis antigens
- GI: Parietal cell or intrinsic factor, ASCA
- Liver: ASMA (smooth muscle), AMA (mitochondrial)
- Kidney: GBM (glomerular basement membrane)
- Skin: BP180 or BP230
The goal is to detect autoimmunity in its early, subclinical stage, as autoantibodies often appear years before the onset of the disease. When someone has multiple autoantibodies, it indicates a heightened autoimmune state (referred to as polyautoimmunity), suggesting they may soon develop an autoimmune disease or that one is already in progress.
Who is this test most suitable for?
- People on a preventive health plan aimed at managing autoimmunity
- Those experiencing chronic stress or infections that could trigger autoimmunity
- Individuals with positive ANA results but no diagnosed disease
- People with family history of autoimmune disease
Clinical Use
This approach is particularly useful for patients with a family history of autoimmune disease or those experiencing vague symptoms that could be autoimmune in nature but lack a definitive diagnosis. Early detection can prompt interventions such as dietary changes, lifestyle modifications, or potentially immunomodulation to help prevent the progression to full-blown disease. Additionally, practitioners may use this information to monitor whether an autoimmune process is affecting new tissues.
About this kit
This product is a physical home blood sample collection kit that is shipped to you. It contains sealed, single-use collection components, instructions, and prepaid return packaging.
Sample collection: This kit is for collection of a blood sample. A trained clinician or phlebotomist assists with the blood draw, which can be arranged at home or at a partner location. The kit includes the collection materials, instructions, and prepaid, pre-addressed return packaging to the accredited partner laboratory.
How it works: Once the laboratory receives your sample, it is processed and your results are delivered to you electronically.
This is a sample collection kit, not a diagnostic service. It does not provide a diagnosis, treatment, or medical advice. Any results should be discussed with a qualified healthcare professional.
